![]() Transient induction of ANG II-dependent malignant hypertension causes sustained elevation of blood pressure and augmentation of the pressor response to ANG II in CYP1A1-REN2 transgenic rats. Reversible toxic effects of the dietary supplement indole-3-carbinol in an immune compromised rodent model: Intestine as the main target. Indole-3-carbinol: anticarcinogen or tumor promoter in brassica vegetables?. Single-dose and multiple-dose administration of indole-3-carbinol to women: pharmacokinetics based on 3,3'-diindolylmethane. Reed G A, Arneson D W, Putnam W C, et al. Estrogen that is not properly metabolized can lead to: weight gain. Preliminary results of the use of indole-3-carbinol for recurrent respiratory papillomatosis. Thorne’s Hormone Advantage (formerly DIM Advantage) combines diindolylmethane (DIM), pomegranate extract, and sulforaphane glucosinolate (SGS from broccoli seed extract) to support balanced hormone health by helping the body metabolize and detoxify excess estrogen. A phase I study of indole-carbinol-3 in women: Tolerability and effects. ![]() ![]() Indole-3-carbinol inhibits the growth of human colon carcinoma cells but enhances the tumor multiplicity and volume of azoxymethane-induced rat colon carcinogenesis. Double-blind randomized placebo-controlled multicenter clinical trial (phase IIa) on diindolylmethane's efficacy and safety in the treatment of CIN: implications for cervical cancer prevention. Indole-3-CarbinolĪshrafian L, Sukhikh G, Kiselev V, Paltsev M, Drukh V, Kuznetsov I, Muyzhnek E, Apolikhina I, Andrianova E.
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